Peer reviewed Publikationen

 

  1. Soufi, L., Kampouris, I.D., Lüneberg, K., Heyde, B.J., Pulami, D., Glaeser, S.P., Siebe, C., Siemens, J., Smalla, K., Grohmann, E., and Gallego, S. Wastewater-borne pollutants influenced the soil ARG and MGE profile but not the bacterial community composition in a changing wastewater irrigation system. 2025. Journal of Hazardous Materials 494, 138680. doi.org/10.1016/j.jhazmat.2025.138680

  2. Heyde, B., Braun, M., Soufi, L., Lüneberg, K., Gallego, S., Amelung, W., Axtmann, K., Bierbaum, G., Glaeser, S., Grohmann, E., Arredondo-Hernández, R., Mulder, I., Pulami, D., Smalla, K., Zarfl C., Siebe, C., and Siemens, J. Transition from irrigation with untreated wastewater to treated wastewater and associated benefits and risks. 2025. Npj Clean Water 8, 6. doi.org/10.1038/s41545-025-00438-6

  3. Heilmann, B., Özipek, S., Stähelin, L., Machava, M., Götz, P., Bader, J., Grohmann, E. Robot-based Automated Isolation and Characterization of a Colicin-producing Escherichia coli-strain with Inhibitory Effect on EPEC. Chemical Engineering Transactions 110, 2024, 355-360. doi: 10.3303/CET24110060

  4. Michaelis, C., Berger, T., Kuhlmann, K., Ghulam, R., Petrowitsch, L., Vecino, M.B., Gesslbauer, B., Pavkov-Keller, T., Keller, W., Grohmann, E. TraN key residues involved in DNA binding affect pIP501 transfer rates in Enterococcus faecalis. Front. Mol. Biosciences 11, 2024. doi: 10.3389/fmolb.2024.1268647

  5. Werner, K.A., Feyen, L., Hübner, T., Brüggemann, N., Prost, K., Grohmann, E. (2023). Fate of Horizontal‐Gene‐Transfer Markers and Beta‐Lactamase Genes During Thermophilic Composting of Human Excreta. Microorganisms 11, 308. doi.org/10.3390/microorganisms11020308

  6. Werner, K.A., Castro-Herrera, D., Yimer, F., Tadesse, M., Kim, D.-G., Prost, K., Brüggemann, N., Grohmann, E. (2023). Microbial Risk Assessment of Mature Compost from Human Excreta, Cattle Manure, Organic Waste, and Biochar. Sustainability 15, 4624. doi.org/10.3390/su15054624

  7. Grohmann, E. (2023). Special Issue “Multidrug-Resistant Bacteria in the Environment, Their Resistance and Transfer Mechanisms. Microorganisms 11, 981. doi.org/10.3390/microorganisms11040981

  8. Michaelis, C., Grohmann, E. (2023). Horizontal gene transfer of antibiotic resistance genes in biofilms. Review. Antibiotics 12, 328. doi.org/10.3390/antibiotics12020328

  9. Siddiqui, Z., Grohmann, E., Malik, A. (2023). Degradation of alkane hydrocarbons by Priestia megaterium ZS16 and sediments consortia with special reference to toxicity and oxidative stress induced by the sediments in the vicinity of an oil refinery. Chemosphere 317, 137886. doi.org/10.1016/j.chemosphere.2023.137886

  10. Werner, K.A., Schneider, D., Poehlein, A., Diederich, N., Feyen, L., Axtmann, K., Hübner, T., Brüggemann, N., Prost, K., Daniel, R., Grohmann, E. (2022). Metagenomic Insights into the Changes of Antibiotic Resistance and Pathogenicity Factor Pools Upon Thermophilic Composting of Human Excreta. Frontiers in Microbiology 13 |Article 826071. doi: 10.3389/fmicb.2022.826071

  11. Berger, T.M.I., Michaelis, C., Probst, I., Sagmeister, T., Petrowitsch, L., Puchner, S., Pavkov-Keller, T., Gesslbauer, B., Grohmann, E., Keller, W. (2022). Small Things Matter: The 11.6-kDa TraB Protein is Crucial for Antibiotic Resistance Transfer Among Enterococci. Front. Mol. Biosci. 9:867136. doi: 10.3389/fmolb.2022.867136

  12. Miguel-Arribas, A., Juan Wu, L., Michaelis, C., Yoshida, K., Grohmann, E., Meijer, W.J.J. (2022). Conjugation operons in Gram-positive bacteria with and without antitermination systems. Microorganisms 10, 587. https://doi.org/10.3390/microorganisms10030587

  13. Ahmed, R., Vaishampayan, A., Achazi, K., Grohmann, E., Haag, R., Wagner, O. (2022). Graphene-based bacterial filtration via electrostatic adsorption. Advanced Materials Interfaces 2101917. doi: 10.1002/admi.202101917

  14. Vaishampayan, A. and Grohmann, E. (2022). Antimicrobials functioning through ROS-mediated mechanisms: current insights. Review. Microorganisms 10, 61. https://doi.org/10.3390/microorganisms10010061

  15. Werner, K., Schneider, D., Poehlein, A., El-Said, K., Wöhrmann, M., Linkert, I., Prost, K., Huebner, T., Brüggemann, N., Daniel, R., Grohmann, E. (2022). Thermophilic composting of human feces: Development of bacterial community composition and antimicrobial resistance gene pool. Frontiers Microbiol., Volume 13 |Article 824834. doi: 10.3389/fmicb.2022.824834

  16. Sally R. Partridge, Virve I. Enne, Elisabeth Grohmann, Ruth M. Hall, Julian I. Rood, Paul H. Roy, Christopher M. Thomas, and Neville Firth (2021).Classifying mobile genetic elements and their interactions from sequence data: The importance of existing biological knowledge. Proc Natl Acad Sci USA. 2021 118 (35) e2104685118; https://doi.org/10.1073/pnas.2104685118

  17. Chopra, A., Mueller, R., Weiner, J., Rosowski, J., Dommisch, J., Grohmann, E., Schaefer, A.S. (2021). BACH1 binding links the genetic risk for severe periodontitis with ST8SIA1 (2021). Journal of Dental Research 1-9. DOI: 10.1177/00220345211017510 journals.sagepub.com/home/jdr

  18. Vaishampayan, A., Ahmed, R., Wagner, O., de Jong, A., Haag, R., Kok, J., Grohmann, E. (2021). Transcriptomic analysis of stress response to novel antimicrobial coatings in a clinical MRSA strain. Materials Science & Engineering C 119, 111578. doi: 10.1016/j.msec.2020.111578.

  19. Wischer, D., Schneider, D., Poehlein, A., Herrmann F., Oruc, H, Meinhardt, J., Wagner, O., Kharin, S., Novikova, N., Haag, R., Daniel, R., Grohmann, E. (2020). Novel antimicrobial cellulose fleece inhibits growth of human-derived biofilm-forming Staphylococci during the SIRIUS19 simulated space mission. Front. Microbiol. 11: 1626. doi: 10.3389/fmicb.2020.01626

  20. Ahmed, R., Vaishampayan, A., Cuellar, L., Wight, D., Donskyi, I., Unger, W., Grohmann, E., Haag, R., Wagner, O. (2020). Multivalent bacteria binding by flexible polycationic micro-sheets matching their surface charge density. Adv. Mater. Interfaces 1902066. doi: 10.1002/admi.201902066.

  21. Sobisch, L.-Y., Rogowski, K. M., Fuchs, J., Schmieder, W., Vaishampayan, A., Oles, P., Novikova, N., Grohmann, E. (2019). Biofilm forming antibiotic resistant Gram-positive pathogens isolated from surfaces on the International Space Station. Front Microbiol. 2019. 10:543. doi: 10.3389/fmicb.2019.00543. eCollection 2019.

  22. Vaishampayan, A., Grohmann, E. (2019). Multi resistant biofilm forming pathogens on the International Space Station: MiniReview. J. Bio. Sc. 44 (5).

  23. Kohler, V., Keller, W., Grohmann, E. (2019). Regulation of Type IV Secretion Systems in Gram-positive Bacteria. Invited Review for Frontiers in Microbiology. Front Microbiol. 10, 1134. doi: 10.3389/fmicb.2019.01134

  24. Kohler, V., Goessweiner-Mohr, N., Aufschnaiter, A., Fercher, C., Probst, I., Pavkov-Keller, T., Hunger, K., Wolinski, H., Büttner, S., Grohmann, E., Keller, W. TraN: A novel repressor of an Enterococcus conjugative type IV secretion system. (2018). Nucleic Acids Res. 46(17):9201-9219. doi: 10.1093/nar/gky671.

  25. Kohler, V., Keller, W., Grohmann, E.Enterococcus adhesin PrgB facilitates type IV secretion by condensation of extracellular DNA. (2018). Mol. Microbiol. 109(3):263-267. doi: 10.1111/mmi.13999.

  26. Kohler, V., Vaishampayan, A., Grohmann, E. Broad-host-range Inc18 plasmids: Occurrence, spread and transfer mechanisms. (2018). Plasmid 99:11-21. doi: 10.1016/j.plasmid.2018.06.001

  27. Grohmann, E., Christie, P.J., Waksman, G., Backert, S. Type IV Secretion in Gram-negative and Gram-positive Bacteria (2018). Mol. Microbiol. 107(4):455-471. doi: 10.1111/mmi.13896.

  28. Vaishampayan, A., de Jong, A., Wight, D.J., Kok, J., Grohmann, E. A novel antimicrobial coating represses biofilm and virulence- related genes in methicillin- resistant Staphylococcus aureus (2018). Front Microbiol. 9:221. doi: 10.3389/fmicb.2018.00221

  29. Clauss-Lendzian, E., Vaishampayan, A., de Jong, A., Landau, U., Meyer, C., Kok, J., Grohmann, E. Stress response of a clinical Enterococcus faecalis isolate subjected to a novel antimicrobial surface coating (2018). Microbiol. Res. 207:53–64. doi: 10.1016/j.micres.2017.11.006

  30. Lüneberg, K., Prado-Pano, B., Broszat, M., Dalkmann, P., Diaz, D., Huebner, J., Amelung, W., Lopez-Vidal, Y., Siemens, J., Grohmann, E., Siebe, C. Water flow paths are hotspots for the dissemination of antibiotic resistance in soil (2018). Chemosphere 193: 1198-1206. doi.org/10.1016/j.chemosphere.2017.11.143

  31. Grohmann, E., Keller, W., Muth, G. Mechanisms of Conjugative Transfer and Type IV Secretion-Mediated Effector Transport in Gram-Positive Bacteria. (2017). Curr Top Microbiol Immunol. 413:115-141. doi: 10.1007/978-3-319-75241-9_5

  32. Garbisu, C., Garaiyurrebaso, O., Lanzén, A., Álvarez-Rodríguez, I., Arana, L., Blanco, F., Smalla, K., Grohmann, E., Alkorta, I. Mobile genetic elements and antibiotic resistance in mine soil amended with organic wastes (2017). Sci Total Environ. 621:725-733. doi: 10.1016/j.scitotenv.2017.11.221.

  33. Garbisu, C., Garaiyurrebaso, O., Epelde, L., Grohmann, E., Alkorta. I. Plasmid-mediated bioaugmentation for the bioremediation of contaminated soils (2017). Front Microbiol. 8:1966. doi: 10.3389/fmicb.2017.01966.

  34. Águila-Arcos, S., Alvarez-Rodriguez, I., Garaiyurrebaso, O., Garbisu, C., Grohmann, E., Alkorta, I. Biofilm-forming clinical Staphylococcus isolates harbor horizontal transfer and antibiotic resistance genes (2017). Front. Microbiol. 8:2018. doi: 10.3389/fmicb.2017.02018.

  35. Laverde, D., Probst, I., Romero-Saavedra, F., Kropec, A., Wobser, D., Keller, W., Grohmann, E., Huebner, J. Targeting type IV secretion system proteins to combat multiresistant Gram-Positive pathogens. (2017). J. Infect. Dis. 215:1836-1845. doi: 10.1093/infdis/jix224

  36. Garaiyurrebaso, O., Garbisu, C., Blanco, F., Lanzén, A., Martín, I., Epelde, L., Becerril, J.M., Jechalke, S., Smalla, K., Grohmann, E., Alkorta, I. Long-term effects of aided phytostabilization on microbial communities of metal-contaminated mine soil. (2017). FEMS Microbiol. Ecol. 93(3). pii: fiw252. doi: 10.1093/femsec/fiw252.

  37. Kohler, V., Probst, I., Aufschnaiter, A., Büttner, S., Schaden, L., Rechberger, G.N., Koraimann, G., Grohmann, E., Keller, W. Conjugative type IV secretion in Gram-positive pathogens: TraG, a lytic transglycosylase and endopeptidase, interacts with translocation channel protein TraM. (2017). Plasmid 91:9-18. doi: 10.1016/j.plasmid.2017.02.002.

  38. Anjum, R., Grohmann, E., Krakat, N. Anaerobic digestion of nitrogen rich poultry manure: Impact of thermophilic biogas process on metal release and microbial resistances. (2017). Chemosphere 168:1637-1647. doi: 10.1016/j.chemosphere.2016.11.132

  39. Probst, I., Vaishampayan, A., Küchler, V., Grohmann, E. Selbst regenerierende antimikrobielle Oberflächenbeschichtung tötet multiresistente Krankheitserreger. (2016). Invited Article for Flugmedizin Tropenmedizin Reisemedizin 23(5):14–17.

  40. Grohmann, E. Goessweiner-Mohr, N., Brantl, S. DNA-binding proteins regulating pIP501 transfer and replication. (2016). Invited Review for Research Topic "Modulating prokaryotic lifestyle by DNA-binding proteins" hosted by Dr(s) Manuel Espinosa, Antonio Juárez, Tatiana Venkova in Frontiers in Molecular Biosciences, section Molecular Recognition. Front. Mol. Biosci. 11.8.2016. http://dx.doi.org/10.3389/fmolb.2016.00042

  41. Fercher, C., Probst, I., Goessweiner-Mohr, N., Arends, K., Grohmann, E., Meyer, N.-H., Zangger, K., Keller, W. VirB8-like protein TraH is crucial for DNA transfer in Enterococcus faecalis (2016). Sci. Rep. 6:24643. doi: 10.1038/srep24643.

  42. Fiedler, S., Bender, J.K., Klare, I., Halbedel, S., Grohmann, E., Szewzyk, U., Werner, G. Tigecycline resistance in clinical isolates of Enterococcus faecium is mediated by an up‑regulation of plasmid-encoded tetracycline determinants tet(L) and tet(M). (2015). J. Antimicrob. Chemother. 71(4):871-881. doi: 10.1093/jac/dkv420.

  43. Jechalke, S., Broszat, M., Lang, F., Siebe, C., Smalla, K., Grohmann E. Effects of 100 years wastewater irrigation on resistance genes, class 1 integrons and IncP-1 plasmids in Mexican soil. (2015). Front. Microbiol. 6:163. eCollection 2015. doi: 10.3389/fmicb.2015.00163.

  44. Guridi, A., Diederich, A.-K., Aguila Arcos, S., Garcia Moreno, M., Blasi, R., Broszat, M., Schmieder, W., Clauss, E., Sakinc-Gueler, T., Andrade, R., Alkorta, I., Meyer, C., Landau, U., Grohmann, E. New antimicrobial contact catalyst killing antibiotic resistant clinical and waterborne pathogens. (2015). Mater. Sci. Eng. C Mater. Biol. Appl. 50:1-11. doi: 10.1016/j.msec.2015.01.080.

  45. Wobser, D., Ali, L., Grohmann, E., Huebner, J., and Sakinc, T. A novel role for D-alanylation of lipoteichoic acid of Enterococcus faecalis in urinary tract infection (2014). PLOS ONE 9(10):e107827. doi: 10.1371/journal.pone.0107827.

  46. Goessweiner-Mohr, N., Eder, M., Hofer, G., Fercher, G., Arends, K., Birner-Gruenberger, R., Grohmann, E., and Keller, W. Structure of the double stranded DNA binding type IV secretion protein TraN from Enterococcus. (2014). Acta Cryst. Section D, Biological Crystallography, 70(9):2376-2389. doi:10.1107/S1399004714014187.

  47. Yamaguchi, N., Roberts, M., Castro, S., Oubre, C., Makimura, K., Leys, N., Grohmann, E., Sugita, T., Ichijo, T., and Nasu, M. Microbial monitoring of crewed habitats in space - current status and future perspectives. (2014). (Invited Review) Microbes Environ. 29(3):250-260. doi:10.1264/jsme2.ME14031.

  48. Broszat, M., Nacke, H., Blasi, R., Siebe, C., Hübner, J., Daniel, R., Grohmann, E. Wastewater irrigation increases abundance of potentially harmful Gammaproteobacteria in soils from Mezquital Valley, Mexico (2014). Appl. Environ. Microbiol. 80(17):5282-5291. doi:10.1128/AEM.01295-14

  49. Goessweiner-Mohr, N., Arends, K., Keller, W., and Grohmann, E. (2014). Conjugation in Gram-positive bacteria. Microbiol. Spectrum 2(4): PLAS-0004-2013. doi:10.1128/microbiolspec.PLAS-0004-2013.

  50. Goessweiner-Mohr, N., Fercher, C., Arends, K., Birner-Gruenberger, D., Laverde-Gomez, D., Huebner, J., Grohmann, E., and Keller, W. The type IV secretion protein TraK from the Enterococcus conjugative plasmid pIP501 exhibits a novel fold. (2014). Acta Cryst. Section D 70(4):1124-1135, doi:10.1107/S1399004714001606

  51. Arends, K., Celik, E.-K., Probst, I., Goessweiner-Mohr, N., Fercher, C., Grumet, L., Soellue, C., Abajy, M.Y., Sakinc, T., Broszat, M., Schiwon, K., Koraimann, G., Keller, W. and Grohmann, E. TraG encoded by the pIP501 type IV secretion system is a two- domain peptidoglycan degrading enzyme essential for conjugative transfer. (2013). J. Bacteriol. 195(19):4436-4444. doi: 10.1128/JB.00721-13

  52. Goessweiner-Mohr, N., Arends, K., Keller, W., and Grohmann, E. Conjugative Type IV Secretion in Gram-positive bacteria. (2013). Plasmid (Invited Review) 70(3):289-302. doi: 10.1016/j.plasmid.2013.06.004

  53. Werner, G., Coque, T. N., Franz, C. M. A. P., Grohmann, E., Hegstad, K., Jensen, L., Sundsfjord, A., van Schaik, W., Weaver, K., and Willems, R.J. Antibiotic resistant Enterococci - tales of a resistance gene trafficker. (2013). Invited Review for Int. J. Med. Microbiol. 303:360-379. doi: 10.1016/j.ijmm.2013.07.004

  54. Goessweiner-Mohr, N., Grumet, L., Arends, K., Pavkov-Keller, T., Gruber, C., Birner-Gruenberger, R., Kropec-Huebner, A., Huebner, J., Grohmann E., and Keller, W. The 2.5 Å structure of the Enterococcus conjugation protein TraM resembles VirB8 type IV secretion proteins. (2013). J. Biol. Chem. 288(3):2018-2028. doi: 10.1074/jbc.M112.421008

  55. Gössweiner-Mohr, N., Grumet, L., Pavkov-Keller, T., Birner-Gruenberger, R., Grohmann, E., and Keller, W. Crystallization and preliminary structure determination of the transfer protein TraM from the Gram-positive conjugative plasmid pIP501. (2013). Acta Crystallographica Struct Biol Cryst Commun. Section F 69(Pt 2):178-183. doi: 10.1107/S2053230X1204928X

  56. Schiwon, K., Arends, K., Preschan, K., Sakinc, T., Hahn, S., van Houdt, R., Werner, G., and Grohmann, E. Comparison of antibiotic resistance, biofilm formation and conjugative transfer of Staphylococcus and Enterococcus isolates from International Space Station (ISS) and Antarctic base Concordia. (2013). Microb. Ecol. 65(3):638-651. doi: 10.1007/s00248-012-0152-8

  57. Dalkmann, P., Broszat, M., Siebe, C., Willaschek, E., Sakinc, T., Huebner, J., Amelung, W., Grohmann, E., and Siemens J. Correction: Accumulation of pharmaceuticals, Enterococcus, and resistance genes in soils irrigated with wastewater for zero to 100 years in Central Mexico. (2012). PLOS ONE 7(12). doi: 10.1371/journal.pone.0051333

  58. Dalkmann, P., Broszat, M., Willaschek, E., Sakinc, T., Huebner, J., Siebe, C., Amelung, W., Grohmann, E., and Siemens, J. Accumulation of pharmaceuticals, Enterococcus, and resistance genes in soils irrigated with wastewater for zero to 100 years in Central Mexico. (2012). PLOS ONE 7(9):e45397. doi: 10.1371/journal.pone.0045397

  59. Gössweiner-Mohr, N., Fercher, C., Abajy, M.Y., Grohmann, E., and Keller, W. Crystallization and preliminary structure determination of the putative transfer protein TraN from Gram-positive conjugative plasmid pIP501. (2012). Acta Cryst. Struct. Biol. Cryst. Commun. Section F 68(11):1402-1405. doi: 10.1107/S2053230X1203861X

  60. Arends, K., Schiwon, K., Sakinc, T., Huebner, J., and Grohmann, E. A GFP-labeled monitoring tool to quantify conjugative plasmid transfer between Gram-positive and Gram-negative bacteria. (2012). Appl. Environ. Microbiol. 78(3):895-899. doi: 10.1128/AEM.06587-11

  61. Anjum, R., Grohmann, E., and Malik A. Exogenous isolation of conjugative plasmids from pesticide contaminated soil. (2012). World J. Microbiol. Biotechnol. 28(2):567-574. doi: 10.1007/s11274-011-0842-y

  62. Levantesi, C., Briancesco, F., Bonadonna, L., Grohmann, E., Toze, S., and Tandoi, V. Salmonella in surface and drinking water: occurrence and waterborne transmission. (2012). Food Research International. Invited Review Special Issue 45(2):587-602. doi: 10.1016/j.foodres.2011.08.020

  63. Kropec, A., Sava, I. G., Vonend, C., Sakinc, T., Grohmann, E., and Huebner, J. Identification of SagA as a novel vaccine target for the prevention of Enterococcus faecium infections. (2011). Microbiology 157(12):3429-3434. doi: 10.1099/mic.0.052689-0

  64. Theilacker, C., Sava, I., Sanchez-Carballo, P., Bao, Y., Kropec, A., Grohmann, E., Holst, O., and Huebner, J. Deletion of the glycosyltransferase bgsB of Enterococcus faecalis leads to a complete loss of glycolipids from the cell membrane and to impaired biofilm formation. (2011). BMC Microbiology 11(1):67. doi: 10.1186/1471-2180-11-67

  65. Anjum, R., Grohmann, E., and Malik, A. Molecular characterization of conjugative plasmids in pesticide tolerant and multi-resistant bacterial isolates from contaminated alluvial soil. (2011). Chemosphere 84(1):175-181. doi: 10.1016/j.chemosphere.2011.03.009

  66. Levantesi, C., La Mantia, R., Masciopinto, C., Böckelmann, U., Ayuso-Gabella, M. N., Salgot, M., Tandoi, V., Van Houtte, E., Wintgens, T., and Grohmann E. Quantification of pathogenic microorganisms and microbial indicators in three wastewater reclamation and managed aquifer recharge facilities in Europe. (2010). Sci. Total Environ. 408(21):4923-4930. doi: 10.1016/j.scitotenv.2010.07.014

  67. Braun, B., Böckelmann, U., Grohmann, E., and Szewzyk, U. Bacterial soil communities affected by water repellency. (2010). Geoderma. 158(3-4):343-351. doi: 10.1016/j.geoderma.2010.05.016

  68. Rangrez, A.Y., Abajy, M.Y., Keller, W., Shouche, Y., and Grohmann, E. Biochemical characterization of three putative ATPases from a new type IV secretion system of Aeromonas culicicula plasmid pAC3249A. (2010). BMC Biochemistry 11:10. doi: 10.1186/1471-2091-11-10

  69. Grohmann, E. Conjugative transfer of the integrative and conjugative element ICEBs1 from B. subtilis likely initiates at the donor cell pole. (2010). Guest commentary. J. Bacteriol. 192(1):23-25. doi: 10.1128/JB.01297-09

  70. Grohmann, E. Autonomous plasmid-like replication of Bacillus ICEBs1: a general feature of integrative conjugative elements? (2010). MicroCommentary Mol. Microbiol. 75(2):261-263. doi: 10.1111/j.1365-2958.2009.07003.x

  71. Borgo, F., Ricci, G., Arends, K., Schiwon, K., Grohmann, E., and Fortina M.G. Evaluation of plasmid content and tetracycline resistance conjugative transfer in Enterococcus italicus strains of dairy origin. (2009). Curr. Microbiol. 59 (3):261-266. doi: 10.1007/s00284-009-9437-y

  72. Böckelmann, U., Dörries, H.-H., Ayuso-Gabella, M. N., Salgot de Marçay, M., Tandoi, V., Levantesi, C., Masciopinto, C., Van Houtte, E., Szewzyk, U., Wintgens, T., and Grohmann, E. Quantitative real-time PCR monitoring of bacterial pathogens and antibiotic resistance genes in three European artificial groundwater recharge systems. (2009). Appl. Environ. Microbiol. 75(1):154-163. doi: 10.1128/AEM.01358-08

  73. Ansari, M. I., Grohmann, E., and Malik, A. Conjugative plasmids in multi-resistant bacterial isolates from Indian soil. (2008). J. Appl. Microbiol. 104(6):1774-1781. doi: 10.1111/j.1365-2672.2008.03733.x

  74. Fortina, M. G., Ricci, G., Borgo, F., Manachini, P. L., Arends, K., Schiwon, K., Abajy, M. Y., and Grohmann, E. A survey on biotechnological potential and safety of the novel Enterococcus species of dairy origin, E. italicus. (2008). Int. J. Food Microbiol. 123(3):204-211. doi: 10.1016/j.ijfoodmicro.2007.12.014

  75. Malik, A., Celik, E.-K., Bohn, C., Boeckelmann, U., Knobel, K., and Grohmann, E. Molecular detection of conjugative plasmids and antibiotic resistance genes in anthropogenic soils from Germany and India. (2008). FEMS Microbiol. Lett. 279(2):207-216. doi: 10.1111/j.1574-6968.2007.01029.x

  76. Abajy, M. Y., Kopec, J., Schiwon, K., Burzynski, M., Döring, M., Bohn, C., and Grohmann, E. A type IV-secretion-like system (T4SLS) is required for conjugative DNA transport of plasmid pIP501 with broad host range in Gram positive bacteria. (2007). J. Bacteriol. 189(7):2487-2496. doi: 10.1128/JB.01670-06

  77. Schaumann, G. E., Braun, B., Kirchner, D., Rotard, W., Szewzyk, U., and Grohmann, E. Influence of biofilms on the water repellency of urban soil samples. (2007). Hydrological Processes (special issue on water repellency) 21(17): 2276-2284. doi: 10.1002/hyp.6778

  78. Alexandrino, M., Grohmann, E., Szewzyk, R., and Szewzyk, U. Application of culture-independent methods to assess the microbial purification efficiency of subsurface flow constructed wetlands. (2007). Water Sci. Technol. 56(3): 217-222. doi: 10.2166/wst.2007.561

  79. Kurenbach, B., Kopeć, J., Mägdefrau, M, Andreas, K., Keller, W., Bohn, C., Abajy, M. Y., and Grohmann, E. The TraA relaxase autoregulates the putative type IV secretion-like system encoded by the broad-host-range Streptococcus agalactiae plasmid pIP501. (2006). Microbiology 152(3):637-645. doi: 10.1099/mic.0.28511-0

  80. Braun, B., Böckelmann, U., Grohmann, E., Szewzyk, U. Polyphasic characterization of the bacterial community in an urban soil profile with in situ and culture dependent methods. (2006). Appl. Soil. Ecol. 31(3):267-279. doi: 10.1016/j.apsoil.2005.07.002

  81. Jäger, F., Grohmann, E., Schaumann, G.E. H NMR relaxometry in natural humous soil samples: Insights in microbial effects on relaxation time distributions. (2006). Plant and Soil 280(1-2):209-222. doi: 10.1007/s11104-005-2821-3

  82. Kopeć, J., Bergmann, A., Fritz, G., Grohmann, E., Keller, W. TraA and its N-terminal relaxase domain of the Gram-positive plasmid pIP501 show specific oriT binding and behave as dimers in solution. (2005). Biochem. Journal 387(2):401-409. doi: 10.1042/BJ20041531

  83. Alexandrino, M., Grohmann, E., Szewzyk, U. Optimization of PCR based methods for rapid detection of pathogens in wastewater samples. (2004). Wat. Res. 38(5):1340-1346. doi: 10.1016/j.watres.2003.12.002

  84. Kurenbach, B., Bohn, C., Prabhu, J., Abudukerim, M., Szewzyk, U., Grohmann, E. Intergeneric transfer of the Enterococcus faecalis plasmid pIP501 to Escherichia coli and Streptomyces lividans and sequence analysis of its tra region. (2003). Plasmid 50(1):86-93. doi: 10.1016/S0147-619X(03)00039-6

  85. Böckelmann, U., Szewzyk, U., Grohmann, E. A new enzymatic method for the detachment of particle associated soil bacteria. (2003). J. Microbiol. Methods 55(1):201-211. doi: 10.1016/S0167-7012(03)00140-8

  86. Grohmann, E., Muth, G., Espinosa, M. Conjugative plasmid transfer in gram-positive bacteria. (2003). Microbiol. Mol. Biol. Rev. 67(2):277-301. doi: 10.1128/MMBR.67.2.277-301.2003

  87. Kurenbach, B., Grothe, D., Farías, M. E., Szewzyk, U., Grohmann, E. The tra-region of the conjugative plasmid pIP501 is organized in an operon with the first gene encoding the relaxase. (2002). J. Bacteriol. 184(6):1801-1805. doi: 10.1128/JB.184.6.1801-1805.2002

  88. Smalla, K., Krogerrecklenfort, E., Heuer, H., Dejonghe, W., Top, E., Osborn, M., Niewint, J., Tebbe, C., Barr, M., Bailey, M., Greated, A., Thomas, C., Turner, S., Young, P., Nikolakopoulou, D., Karagouni, A., Wolters, A., van Elsas, J. D., Dronen, K., Sandaa, R., Borin, S., Prabhu, J., Grohmann, E., Sobecky, P. PCR-based detection of mobile genetic elements in total community DNA. (2000). Microbiology 146(5):1256-1257. doi: 10.1099/00221287-146-5-1255

  89. Grohmann, E., Guzmán, L., Espinosa, M. Mobilisation of the streptococcal pMV158: interactions of MobM protein with its cognate oriT DNA region. (1999). Mol. Gen. Genet. 261(4-5):707-715. doi: 10.1007/s004380050021

  90. Farías, M. E., Grohmann, E., Espinosa, M.Expression of the mobM gene of the streptococcal plasmid pMV158 in Lactococcus lactis subsp. lactis. (1999). FEMS Microbiol. Lett. 176(2):403-410. doi: 10.1111/j.1574-6968.1999.tb13691.x

  91. Grohmann, E., Moscoso, M., Zechner, E.L., del Solar, G., Espinosa, M. In vivo definition of the functional origin of leading strand replication on the lactococcal plasmid pFX2. (1998). Mol. Gen. Genet. 260(1):38-47. doi: 10.1007/s004380050882

  92. Zechner, E.L., Prueger, H., Grohmann, E., Espinosa, M., Hoegenauer, G.Specific cleavage of chromosomal and plasmid DNA strands in Gram-positive and Gram-negative bacteria can be detected in vitro with nucleotide resolution. (1997). Proc. Natl. Acad. Sci. USA. 94(14):7435-7440. doi: 10.1073/pnas.94.14.7435

  93. Grohmann, E., Zechner, E.L., Espinosa, M.Determination of specific DNA strand discontinuities with nucleotide resolution in exponentially growing bacteria harbouring rolling circle-replicating plasmids. (1997). FEMS Microbiol. Lett. 152(2):363-369. doi: 10.1111/j.1574-6968.1997.tb10447.x

  94. Grohmann, E., Stanzer, T., Schwab, H. The ParB nuclease encoded by the RP4 par region is a Ca2+ dependent nuclease linearizing circular DNA substrates. (1997). Microbiology 143(12):3889-3898. doi: 10.1099/00221287-143-12-3889

  95. Jensen, R.B., Grohmann, E., Schwab, H., Diaz-Orejas, R., Gerdes, K.Comparison of ccd of F, parDE of RP4, and parD of R1 using a novel conditional replication control system of plasmid R1. (1995). Mol. Microbiol. 17(2):211-220. doi: 10.1111/j.1365-2958.1995.mmi_17020211.x

  96. Eberl, L., Kristensen, C., Givskov, M., Grohmann, E., Gerlitz, M., Schwab, H.Analysis of the multimer resolution system encoded by the parCBA operon of broad-host-range plasmid RP4. (1994). Mol. Microbiol. 12(1):131-142. doi: 10.1111/j.1365-2958.1994.tb01008.x

  97. Haigermoser, C., Chen, G.Q., Grohmann, E., Hrabak, O., Schwab, H. Stabilization of plasmid vectors by the partitioning function of broad-host-range plasmid RP4. (1993). J. Biotechnol. 28(2-3):291-299. doi: 10.1016/0168-1656(93)90054-U

 

Further Publications

 

  1. Siemens, J., Siebe, C., Heyde, B., Mulder, I., Grohmann, E., Soufi, L., Gallego, S., Smalla, K., Prado, B. (2023). Functioning soil is the basis for sustainable wastewater irrigation. Agricultural & Food Policy. Welternährung. Das Fachjournal der Welthungerhilfe 12/2023

  2. Grohmann, E.; Vaishampayan, A., Holländer, M.-A., Muratov, E., Wischer D.; Schneider, D.; Poehlein, A.; Wagner, O; Kharin, S.; Haag, R.; Daniel, R.; Moeller, R. (2021): AGXX® inhibits growth of human-derived pathogens during the SIRIUS-2019 isolation and affects the germinated spores of Bacillus subtilis. Proceedings of the 11th International Space Safety Conference (IAASS), Rotterdam, the Netherlands (online), October 2021, p. 703-709.

  3. Landau, U., Meyer, C., Grohmann, E. AGXX (2017): Beitrag der Oberflächentechnik zur Vermeidung von Biofilmen (Teil 1) Galvanotechnik 5: 885-890.

  4. Landau, U., Meyer, C., Grohmann, E. AGXX (2017): Beitrag der Oberflächentechnik zur Vermeidung von Biofilmen (Teil 2) Galvanotechnik 6: 1110-1121.

  5. Grohmann, E., Meyer, C., Landau, U. Der Kontakt Katalysator AGXX tötet multiresistente klinische Staphylokokken und Enterokokken. (2015). M·O·T - Medizinisch-Orthopädische Technik, Sonderheft MRSA, pp. 62-64.

  6. Böckelmann, U., Dörries, H.-H., Szewzyk, U., Grohmann, E. Quantitative PCR monitoring of bacterial pathogens and antibiotic resistance genes in the artificial groundwater recharge systems Torreele, Sabadell and Nardo. Final Dissemination Workshop on Water Reclamation and Aquifer Recharge, 5.-6.9.2008, Maribor, Slovenia. In Water Reclamation and Aquifer Recharge, IEI (Institute for Ecological Engineering), Maribor, Slovenia, pp. 48-49. ISBN: 978-961-238-954-3.

  7. Grohmann, E. Plasmidtransfer in Gram-positiven Bakterien: ein neuer Typ IV-Sekretionsmechanismus? BIOspektrum 3/2004, p. 282.

  8. Farías, M.E., Ruiz-Maso, J.A., Grohmann, E., Guzmán, L., Espinosa, M. Mechanisms of DNA-bound proteins in prokaryotes. Plasmid pMV158 encodes two proteins with nicking-closing activities: RepB, the initiator of replication, and MobM, involved in mobilisation. (2001). In Fundación Juan March (ed.), Mechanisms of DNA-bound proteins in prokaryotes, Fundación Juan March, Madrid, Spain, p. 63-64.

  9. Grohmann, E., Eberl, L., Kristensen, C., Schwab, H. Plasmid stability in Gram-negative bacteria: Molecular structure and function of the partitioning system of the broad-host-range plasmid RP4. Proceedings of the Sixth European Congress on Biotechnology, Florence, Italy, June 1994, p. 199-202.

 

Book Chapters and Co-Edition of Books /Special Issues of Scientific Journals


 

  1. Brom, S., Llosa, M., Grohmann, E. (2021). Co-Editor of Special Issue of publications of Early Career Researchers (ECR):113, Plasmid, Elsevier.

  2. Grohmann, E., Kohler, V., Vaishampayan, A. (2019). Book chapter: Acquired resistance from gene transfer. In Antibiotic Drug Resistance. José Luis Capelo-Martinez, Gilberto Igrejas. Editors. Wiley, Hoboken, New Yersey, USA. p. 141-166. ISBN: 978-1-119-28252-5.

  3. Kohler, V., Vaishampayan, A., Grohmann, E. (2019). Book chapter: Problematic Groups of Multidrug Resistant Bacteria and their Resistance Mechanisms. In Antibacterial Discovery from Natural Products to Nanomaterials: Recent trends to combat the MDR problem. Iqbal Ahmad, Kendra K.P. Editors. Springer Nature, Singapore. p. 25-69. ISBN 978-981-13-9870-4.

  4. Grohmann, E., Keller, W., Muth, G. (2017). Book chapter: Mechanisms of Conjugative Transfer and Type IV Secretion-Mediated Effector Transport in Gram-Positive Bacteria. In Type IV Secretion in Gram-negative and Gram-positive Bacteria. Steffen Backert, Elisabeth Grohmann. Editors. Springer press. ISBN 978-3-319-75241-9.

  5. Grohmann, E., Vaishampayan, A. (2017). Book chapter: Techniques to study biofilms and their characterization: Microscopy to advanced imaging systems in vitro and in situ. In Biofilms in Plant and Soil Health: Fundamentals and current research. Iqbal Ahmad. Editor. Wiley-Blackwell press, New Jersey, USA, ISBN: 9781119246343. http://eu.wiley.com/WileyCDA/WileyTitle/productCd-1119246342.html

  6. Broszat, M., Grohmann, E. (2017). Book chapter: Antimicrobial resistance spread mediated by wastewater irrigation: the Mezquital Valley case study. In Antimicrobial Resistance in the Wastewater Treatment Process. Patricia Keen & Raphaël Fugère. Editors. John Wiley & Sons, Inc. NJ, USA ISBN: 978-1-119-19243-5.

  7. Goessweiner-Mohr, N., Arends, K., Keller, W., Grohmann, E. (2015). Book chapter: Conjugation in Gram-Positive Bacteria. In Plasmids - Biology and Impact in Biotechnology and Discovery. Marcelo E. Tolmasky, Juan C. Alonso Editors. doi:10.1128/microbiolspec.PLAS-0004-2013. ASM Press, Washington, D.C.

  8. Broszat, M., Grohmann, E. (2014). Book chapter and co-editor: Spread of antibiotic resistance in the environment: Impact on human health. In Environmental Deterioration and Human Health: Natural and Anthropogenic Determinants. Abdul Malik, Elisabeth Grohmann, Rais Akhtar Editors. ISBN 978-94-007-7890-0. Springer press, New York

  9. Broszat, M., Grohmann, E. (2014). Book chapter: Horizontal gene transfer in biofilm and planktonic modes. In Antibiofilm agents: from diagnosis to treatment and prevention. Iqbal Ahmad, Kendra Rumbaugh Editors. ISBN 978-3-642-53832-2. Springer press, New York

  10. Grohmann, E. (2013). Book chapter and co-editor: Conjugative plasmids in anthropogenic soils. In Management of Microbial Resources in the Environment. Abdul Malik, Elisabeth Grohmann, Madalena Alves Editors. ISBN 978-94-007-5931-2. Springer press, New York

  11. V. Tandoi, C. Levantesi, S. Toze, U. Böckelmann, M. Divizia, N. Ayuso, M. Salgot, R. La Mantia, E. Grohmann. (2012). Book chapter: Water quality analysis – microbiological hazards. In Advances in Water Reclamation Technologies for Safe Managed Aquifer Recharge: Christian Kazner, Thomas Wintgens, Peter Dillon Editors. ISBN: 9781843393443. IWA Publishing, London, UK

  12. Grohmann, E. (2011). Book chapter: Horizontal gene transfer between bacteria under natural conditions. In Microbes and Microbial Technology: Agricultural and Environmental Applications: Iqbal Ahmad, Farah Ahmad, John Pichtel Editors. ISBN 978-1-4419-7930-8, e-ISBN 978-1-4419-7931-5. Springer New York Dordrecht Heidelberg London© Springer Science+Business Media, LLC 2011

  13. Grohmann, E., Arends, K. (2011). Book chapter and co-editor: Molecular detection of resistance and transfer genes in environmental samples. In Environmental Protection Strategies for Sustainable Development. Abdul Malik and Elisabeth Grohmann Editors. Springer press, New York, ISBN: 978-94-007-1590-5

  14. Ansari, M.I., Schiwon, K., Malik, A., Grohmann, E. (2011). Book chapter and co-editor: Biofilm formation by environmental bacteria. In Environmental Protection Strategies for Sustainable Development. Abdul Malik and Elisabeth Grohmann Editors. Springer press, New York, ISBN: 978-94-007-1590-5

  15. Malik, A., Rahman, M., Ansari, M.I., Masood, F., Grohmann, E. (2011). Book chapter and co-editor: Environmental Protection Strategies: An Overview. In Environmental Protection Strategies for Sustainable Development. Abdul Malik and Elisabeth Grohmann Editors. Springer press, New York, ISBN: 978-94-007-1590-5

  16. Grohmann, E. (2006). Book chapter: Mating cell-cell channels in conjugating bacteria. (2006). In Cell-Cell Channels. Baluska, F., Volkmann, D., and Barlow, P.W., Editors. Landes Biosciences, Georgetown, Texas, pp. 21-38. ISBN: 1-58706-065-5

 

Manuscripts (under revision or in preparation)

 

  1. Kuhlmann, K., Berger, T., Stallinger, A., Michaelis, C., Kohler, V., Lammer, A., Fercher, C., Probst, I., Pavkov-Keller, T., Grohmann, E., Keller, W. Structure and role of the type IV secretion factor TraF in conjugative plasmid transfer of pathogenic Firmicutes (in preparation)

  2. Wischer, D., Hadersbeck, R., Morad, L., Grohmann, E. Unveiling the potent antibacterial activity of AGXX surfaces: A quantitative evaluation using a modified JIS Z 2801 assay (in preparation)

 

Patents

 

  1. Neuartiges Antigen von Enterokokkenpathogenen und ihre Verwendung als Impfstoffkomponenten für Therapie und/oder Prophylaxe EP20100190167. Novel antigen of enterococcal pathogens and use thereof as vaccine component for therapy and/or prophylaxis EP 2450053 B1 (granted)